| Title |
Treatment for HIV-Infected Patients to Induce Long-Term Non-Progressor with Constant Drug Dosage |
| Authors |
김진영(Kim Jinyoung) ; 김원희(Kim Won Hee) ; 고지현(Ko Ji Hyun) ; 정한별(Chung Han Byul) ; 정정주(Chung Chung Choo) |
| Abstract |
This paper presents a therapy that uses a constant drug dosage for leading HIV-infected patient to LTNP (Long-Term Non-Progressor). Based on analysis of CTLp (Cytotoxic T Lymphocyte precursor) concentration at equilibrium point and its bifurcation, we found the therapy with a drug whose efficacy is less than a certain level brings higher CTLp concentration at the equilibrium point. We observed a treatment with constant drug dosage whose efficacy is less than full treatment may lead HIV-infected patient to LTNP. It turns out that the treatment whose efficacy is less than full treatment is better in the point of performance on controllability. |